PDB ID: 5ZG6
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Structure summary
Code : | 5ZG6 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal structure of beta-lactamase PenP mutant-E166Y in complex with cephaloridine as "post-acylation" intermediate | ||||||||||||
Release Data : | 2019-03-20 | ||||||||||||
Compound : |
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Source : |
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Authors : | Pan, X., Zhao, Y. | ||||||||||||
Keywords : | class A beta-lactamase, antibiotic resistance, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.00 Å ) | ||||||||||||
Citation : |
The hydrolytic water molecule of Class A beta-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis.
He, Y.,Lei, J.,Pan, X.
et al.
PubMed: 32576842 |
Reaction
Chain : | B, A | ||||||||
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UniProt : | P00808 (BLAC_BACLI) | ||||||||
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