PDB ID: 5ZG2
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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9C0 | 9-(4-~{tert}-butylphenyl)-3,4-dihydropyrido[2,1-C][1,2,4]thiadiazine 2,2-dioxide | PoSSuM | |||
ACT | Acetate ion | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
ZK1 | {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2h)-yl]methyl}phosphonic acid | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 5ZG2
Structure summary
Code : | 5ZG2 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSPORT PROTEIN | ||||||||||||
Title : | Crystal structure of the GluA2o LBD in complex with ZK200775 and Compound-2 | ||||||||||||
Release Data : | 2019-01-16 | ||||||||||||
Compound : |
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Source : |
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Authors : | Sogabe, S., Igaki, S., Hirokawa, A., Zama, Y., Lane, W., Snell, G. | ||||||||||||
Keywords : | AMPA RECEPTOR LIGAND-BINDING DOMAIN, ALLOSTERIC MODULATION COMPLEX, MEMBRANE PROTEIN, TRANSPORT PROTEIN | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.25 Å ) | ||||||||||||
Citation : |
TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window.
Kunugi, A.,Tanaka, M.,Suzuki, A.
et al.
PubMed: 30209408 |
Reaction
Chain : | A, B |
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UniProt : | P42262 (GRIA2_HUMAN) |
Reaction : | - |