Brand  (β version)

PDB ID: 5ZDP

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Ligands
Code Name Style Show Link
FE Fe (III) ion PoSSuM
OH Hydroxide ion PoSSuM
OXY Oxygen molecule PoSSuM
9AU 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one PoSSuM
Non-standard Residues
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Structure summary

Code : 5ZDP   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ferulenol
Release Data : 2019-02-27
Compound :
mol_id molecule chains
1 Alternative oxidase, mitochondrial A,B,C,D
Source :
mol_id organism_scientific expression_system
1 Trypanosoma brucei brucei  (taxid:5702) Escherichia coli  (taxid:562)
gene: AOX
expression_system_strain: FN102
expression_system_vector_type: PLASMID
expression_system_plasmid: PET15B
Authors : Shiba, T., Inaoka, D.K., Takahashi, G., Tsuge, C., Kido, Y., Young, L., Ueda, S., Balogun, E.O., Nara, T., Honma, T., Tanaka, A., Inoue, M., Saimoto, H., Harada, S., Moore, A.L., Kita, K.
Keywords : MEMBRANE BOUND DIIRON PROTEIN, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.71 Å )
Citation :

Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.

Shiba, T.,Inaoka, D.K.,Takahashi, G.  et al.
(2019)  Biochim Biophys Acta Bioenerg  1860 : 375 - 382

PubMed: 30910528
DOI: 10.1016/j.bbabio.2019.03.008

Reaction

Chain : A, B, C, D
UniProt : Q26710 (AOX_TRYBB)
Reaction : -
Cofactor: Evidence: Note:
Fe cation ECO:0000269 | PubMed:23487766
Binds 2 iron ions per subunit.