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Ligands
Code Name Style Show Link
96X N-{8-hydroxy-4-[(1h-imidazol-1-yl)methyl]quinolin-2-yl}acetamide
Non-standard Residues
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Glycosylation
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Code : 5Z5V   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION/INHIBITOR
Title : The first bromodomain of BRD4 with compound BDF-1253
Release Data : 2019-01-23
Compound :
mol_id molecule chains synonym
1 Bromodomain-containing protein 4 A Protein HUNK1
fragment: BD1 domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: BRD4, HUNK1
Authors : Zhang, H., Luo, C.
Keywords : BRD4, Inhibitor, Complex, PROTEIN BINDING, TRANSCRIPTION-INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.660 Å )
Citation :

Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.

Chen, W.,Zhang, H.,Chen, Z.  et al.
(2018)  Oncogenesis  7 : 83 - 83

PubMed: 30385738
DOI: 10.1038/s41389-018-0093-z

Chain : A
UniProt : O60885 (BRD4_HUMAN)
Reaction : -