Brand  (β version)

PDB ID: 5Z4P

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Ligands
Code Name Style Show Link
97O 6,7,8-trimethoxy-1-(4-methoxyphenyl)-4,5-dihydro-2~{H}-benzo[E]indazole PoSSuM
ACP Phosphomethylphosphonic acid adenylate ester PoSSuM
CA Calcium ion PoSSuM
GDP Guanosine-5'-diphosphate PoSSuM
GOL Glycerol PoSSuM
GTP Guanosine-5'-triphosphate PoSSuM
IMD Imidazole PoSSuM
MES 2-(N-morpholino)-ethanesulfonic acid PoSSuM
MG Magnesium ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5Z4P   PDBj   RCSB PDB   PDBe
Header : OXYGEN TRANSPORT
Title : Crystal structure of tubulin-stathmin-TTL-Compound TCA complex
Release Data : 2019-01-16
Compound :
mol_id molecule chains synonym
1 Tubulin alpha-1B chain A,C Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
fragment: UNP residues 1-438
mol_id molecule chains
2 Tubulin beta-2B chain B,D
fragment: UNP residues 1-425
mol_id molecule chains synonym
3 Stathmin-4 E Stathmin-like protein B3,RB3
mol_id molecule chains
4 Tubulin tyrosine ligase F
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
2 Bos taurus  (taxid:9913) Bovine
mol_id organism_scientific organism_common
3 Rattus norvegicus  (taxid:10116) Rat
mol_id organism_scientific organism_common
4 Gallus gallus  (taxid:9031) Chicken
Authors : Zhang, H., Luo, C.
Keywords : Tubulin, OXYGEN TRANSPORT
Exp. method : X-RAY DIFFRACTION ( 2.5 Å )
Citation :

Discovery and Design of novel Tubulin inhibitors

Zhang, H.,Luo, C.
To Be Published 

Reaction

Chain : A, C
UniProt : P81947 (TBA1B_BOVIN)
Reaction: EC: Evidence:
Physiological Direction:
GTP + H2O = GDP + H(+) + phosphate - UniProtKB:P68363
left-to-right
Chain : B, D
UniProt : Q6B856 (TBB2B_BOVIN)
Reaction : -
Chain : E
UniProt : P63043 (STMN4_RAT)
Reaction : -
Chain : F
UniProt : E1BQ43
Reaction : -