Brand  (β version)

PDB ID: 5YY6

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Ligands
Code Name Style Show Link
94L 3-(2,6-dimethylphenyl)-1-methyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione PoSSuM
CO Cobalt (II) ion PoSSuM
Non-standard Residues
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Structure summary

Code : 5YY6   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of Arabidopsis thaliana HPPD truncated mutant complexed with Benquitrione
Release Data : 2019-01-16
Compound :
mol_id molecule chains synonym
1 4-hydroxyphenylpyruvate dioxygenase A 4-hydroxyphenylpyruvic acid oxidase,HPPDase
ec: 1.13.11.27
Source :
mol_id organism_scientific organism_common expression_system
1 Arabidopsis thaliana  (taxid:3702) Mouse-ear cress Escherichia coli 'BL21-Gold(DE3)pLysS AG'  (taxid:866768)
gene: HPD, PDS1, At1g06570, F12K11.9
expression_system_strain: BL21-Gold(DE3)pLysS AG
Authors : Yang, W.C., Chen, J.N., Yang, G.F.
Keywords : 4-hydroxyphenylpyruvate dioxygenase, Type I tyrosinemia, drug discovery, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.401 Å )
Citation :

Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery.

Lin, H.Y.,Chen, X.,Chen, J.N.  et al.
(2019)  Research (Wash D C)  2019 : 2602414 - 2602414

PubMed: 31549053
DOI: 10.34133/2019/2602414

Reaction

Chain : A
UniProt : P93836 (HPPD_ARATH)
Reaction: EC: Evidence:
Physiological Direction:
3-(4-hydroxyphenyl)pyruvate + O2 = CO2 + homogentisate 1.13.11.27 PubMed:15301540
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