Brand  (β version)

PDB ID: 5YWH

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Ligands
Code Name Style Show Link
92U [1,3-diethyl-2,2-bis(oxidanylidene)-2$L^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone PoSSuM
FE Fe (III) ion PoSSuM
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Structure summary

Code : 5YWH   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508
Release Data : 2019-01-16
Compound :
mol_id molecule chains synonym
1 4-hydroxyphenylpyruvate dioxygenase A,B 4-hydroxyphenylpyruvic acid oxidase,HPPDase
ec: 1.13.11.27
Source :
mol_id organism_scientific organism_common expression_system
1 Arabidopsis thaliana  (taxid:3702) Mouse-ear cress Escherichia coli 'BL21-Gold(DE3)pLysS AG'  (taxid:866768)
gene: HPD, PDS1, At1g06570, F12K11.9
expression_system_strain: BL21-Gold(DE3)pLysS AG
Authors : Yang, W.C., Lin, H.Y.
Keywords : 4-hydroxyphenylpyruvate dioxygenase, Type 1 Tyrosinemia, drug discovery, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.720 Å )
Citation :

Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508

Yang, W.C.,Lin, H.Y.
To be published 

Reaction

Chain : A, B
UniProt : P93836 (HPPD_ARATH)
Reaction: EC: Evidence:
Physiological Direction:
3-(4-hydroxyphenyl)pyruvate + O2 = CO2 + homogentisate 1.13.11.27 PubMed:15301540
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