Brand  (β version)

PDB ID: 5XR3

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Ligands
Code Name Style Show Link
GLV Glyoxylic acid PoSSuM
Non-standard Residues
Code Name Show
CGV S-[(R)-carboxy(hydroxy)methyl]-L-cysteine
Glycosylation
Code Name Emphasize
Modification
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Structure summary

Code : 5XR3   PDBj   RCSB PDB   PDBe
Header : CHAPERONE
Title : SAV0551 with glyoxylate
Release Data : 2017-11-01
Compound :
mol_id molecule chains synonym
1 Protein/nucleic acid deglycase HchA A,B,C,D,E,F,G,H Maillard deglycase,Protein deglycase HchA
ec: 3.1.2.-,3.5.1.124
Source :
mol_id organism_scientific expression_system
1 Staphylococcus aureus (strain Mu50 / ATCC 700699)  (taxid:158878) Escherichia coli  (taxid:562)
strain: Mu50 / ATCC 700699
gene: hchA, SAV0551
Authors : Kim, H.J., Kwon, A.R., Lee, B.J.
Keywords : Hsp31, chaperone, glyoxalase III
Exp. method : X-RAY DIFFRACTION ( 3.01 Å )
Citation :

Structural and functional studies of SAV0551 fromStaphylococcus aureusas a chaperone and glyoxalase III.

Kim, H.J.,Lee, K.Y.,Kwon, A.R.  et al.
(2017)  Biosci. Rep.  37

PubMed: 29046369
DOI: 10.1042/BSR20171106

Reaction

Chain : A, B, C, D, E, F, G, H
UniProt : P64312 (HCHA_STAAM)
Reaction: EC: Evidence:
Physiological Direction:
N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] + H2O = lactate + L-arginyl-[protein] + H(+) 3.5.1.124 HAMAP-Rule:MF_01046
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N(6)-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] + H2O = lactate + L-lysyl-[protein] + H(+) 3.5.1.124 HAMAP-Rule:MF_01046
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S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] + H2O = lactate + L-cysteinyl-[protein] + H(+) 3.5.1.124 HAMAP-Rule:MF_01046
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N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] + H2O = L- arginyl-[protein] + glycolate + H(+) 3.5.1.124 HAMAP-Rule:MF_01046
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N(6)-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein] + H2O = glycolate + L-lysyl-[protein] + H(+) 3.5.1.124 HAMAP-Rule:MF_01046
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S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] + H2O = glycolate + L-cysteinyl-[protein] + H(+) 3.5.1.124 HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxopropyl)-GTP + H2O = lactate + GTP + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxopropyl)-GDP + H2O = lactate + GDP + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxopropyl)-GMP + H2O = lactate + GMP + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxoethyl)-dGTP + H2O = dGTP + glycolate + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxoethyl)-GTP + H2O = glycolate + GTP + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxoethyl)-GDP + H2O = glycolate + GDP + H(+) - HAMAP-Rule:MF_01046
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N(2)-(1-hydroxy-2-oxoethyl)-GMP + H2O = glycolate + GMP + H(+) - HAMAP-Rule:MF_01046
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an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O = a guanosine in RNA + lactate + H(+) - HAMAP-Rule:MF_01046
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an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + lactate + H(+) - HAMAP-Rule:MF_01046
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an N(2)-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O = a guanosine in RNA + glycolate + H(+) - HAMAP-Rule:MF_01046
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an N(2)-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + glycolate + H(+) - HAMAP-Rule:MF_01046
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