Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
DC 2'-deoxycytidine-5'-monophosphate
Code : 5WRN
Header : TRANSFERASE
Title : Human thymidylate synthase complexed with dCMP
Release Data : 2016-12-14
Compound :
mol_id molecule chains synonym
1 Thymidylate synthase B,A,C,D,E,F TSase
ec: 2.1.1.45
fragment: UNP residues 26-313
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: TYMS, TS, OK/SW-cl.29
Authors : Chen, D., Nordlund, P.
Keywords : Complex, nucleotide, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.3900 Å )
Citation :

Human thymidylate synthase complexed with dCMP

Almqvist, H.,Axelsson, H.,Jafari, R.  et al.
To Be Published 

Chain : B, A, C, D, E, F
UniProt : P04818 (TYSY_HUMAN)
Reaction : 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.