Het-PDB Navi2 (PDB: 5WIC)

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Download interaction data: 5WIC

Code :

5WIC PDBj RCSB PDB PDBe

Header :

PROTEIN TRANSPORT

Title :

TraE protein in complex with 2-Furoic Acid (FOA)

Release Data :

2017-11-15

Compound :

mol_id	molecule	chains	synonym
1	Conjugal transfer protein	A,B,C,D	Conjugal transfer protein TraE,TraE,TraE protein,Inner membrane protein forms channel for type IV secretion of T-DNA complex,VirB8,Type IV secretion of T-DNA VirB8,Type IV secretion system protein VirB8
	fragment: residues 70-232

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli (taxid:469008)
	gene: traE, B634_00049, BE957_00530, ECONIH1_27615, pec386IL_00125, pEcNDM0_00049, pHKU1_33, pKC394-028, pKC396-021, pMUR050_041, pN3_023 expression_system_cell_line: BL21(DE3)STAR expression_system_plasmid: PHT

Authors :

Casu, B., Arya, T., Bessette, B., Baron, C.

Keywords :

Type IV Secretion System, Fragment-Based Drug Design, Complex, Inhibitor, Antimicrobial Resistance, Bacterial secretion, VirB, PROTEIN TRANSPORT

Exp. method :

X-RAY DIFFRACTION ( 2.55 Å )

Citation :

Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101.

Casu, B.,Arya, T.,Bessette, B. et al.
(2017) Sci Rep 7 : 14907 - 14907

PDB ID: 5WIC