Brand  (β version)

PDB ID: 5WI5

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Ligands
Code Name Style Show Link
0V5 (2r)-2-(phosphonooxy)propanoic acid PoSSuM
MG Magnesium ion PoSSuM
EPU Uridine-diphosphate-2(N-acetylglucosaminyl) butyric acid PoSSuM
Non-standard Residues
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Structure summary

Code : 5WI5   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : 2.0 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Streptococcus pneumoniae in Complex with Uridine-diphosphate-2(N-acetylglucosaminyl) butyric acid, (2R)-2-(phosphonooxy)propanoic acid and Magnesium.
Release Data : 2017-08-02
Compound :
mol_id molecule chains synonym
1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 A,B,C,D Enoylpyruvate transferase 1,UDP-N-acetylglucosamine enolpyruvyl transferase 1,EPT 1
ec: 2.5.1.7
Source :
mol_id organism_scientific expression_system
1 Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)  (taxid:170187) Escherichia coli  (taxid:469008)
strain: ATCC BAA-334 / TIGR4
gene: murA1, murA, SP_1966
expression_system_strain: BL21 (DE3) magic
expression_system_vector_type: plasmid
expression_system_plasmid: pMCSG53
Authors : Minasov, G., Shuvalova, L., Dubrovska, I., Kiryukhina, O., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Keywords : Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Uridine-diphosphate-2(n-acetylglucosaminyl) butyric acid, (2R)-2-(phosphonooxy)propanoic acid, Magnesium, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.00 Å )
Citation :

2.0 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Streptococcus pneumoniae in Complex with Uridine-diphosphate-2(n-acetylglucosaminyl) butyric acid, (2R)-2-(phosphonooxy)propanoic acid and Magnesium.

Minasov, G.,Shuvalova, L.,Dubrovska, I.  et al.
To Be Published 

Reaction

Chain : A, B, C, D
UniProt : Q97NQ4 (MURA1_STRPN)
Reaction: EC: Evidence:
Physiological Direction:
phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine 2.5.1.7 HAMAP-Rule:MF_00111
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