Het-PDB Navi2 (PDB: 5WHH)

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Ligands
Code	Name		Style	Show	Link
CL	Chloride ion				PoSSuM

Non-standard Residues
Code	Name	Show
0EH	(2r)-2-amino-2-methylnonanoic acid
MK8	2-methyl-L-norleucine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
AQ7	N-[(3r)-1-propanoylpiperidine-3-carbonyl]-L-alanine
NH2	Amino group

Download interaction data: 5WHH

Code :

5WHH PDBj RCSB PDB PDBe

Header :

APOPTOSIS

Title :

Crystal Structure of Bcl-2-related protein A1 in complex with stapled peptide (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2)

Release Data :

2018-01-17

Compound :

mol_id	molecule	chains	synonym
1	Bcl-2-related protein A1	A	Bcl-2-like protein 5,Bcl2-L-5,Hemopoietic-specific early response protein,Protein BFL-1,Protein GRS
	mutation: C4S, C19S

mol_id	molecule	chains
2	(AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2)	B

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: BCL2A1, BCL2L5, BFL1, GRS, HBPA1 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid

mol_id	organism_scientific
2	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Seo, H.-S., Dhe-Paganon, S.

Keywords :

apoptosis, stapled peptide

Exp. method :

X-RAY DIFFRACTION ( 2.38 Å )

Citation :

Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.

Harvey, E.P.,Seo, H.S.,Guerra, R.M. et al.
(2018) Structure 26 : 153 - 160.e4

PDB ID: 5WHH