Het-PDB Navi2 (PDB: 5WEO)

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Ligands
Code	Name		Style	Show	Link
CYZ	Cyclothiazide				PoSSuM
GLU	Glutamic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5WEO

Code :

5WEO PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Activated GluA2 complex bound to glutamate, cyclothiazide, and STZ in digitonin

Release Data :

2017-08-02

Compound :

mol_id	molecule	chains	synonym
1	Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit chimera	A,B,C,D	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2
	fragment: UNP P19491 residues 25-847, UNP O88602 2-208 linked via LINKER GT mutation: N241E, V382L, G384E, N385D, V758L

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Mus musculus (taxid:10090)	Mouse	Homo sapiens (taxid:9606)
	gene: Cacng2, Stg expression_system_cell_line: HEK293 gnti-

Authors :

Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I.

Keywords :

Ion channel, TRANSPORT PROTEIN

Exp. method :

ELECTRON MICROSCOPY ( 4.2 Å )

Citation :

Channel opening and gating mechanism in AMPA-subtype glutamate receptors.

Twomey, E.C.,Yelshanskaya, M.V.,Grassucci, R.A. et al.
(2017) Nature 549 : 60 - 65

PDB ID: 5WEO