Het-PDB Navi2 (PDB: 5W9D)

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Ligands
Code	Name		Style	Show	Link
9XY	Endoxifen				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5W9D

Code :

5W9D PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen

Release Data :

2017-10-11

Compound :

mol_id	molecule	chains	synonym
1	Estrogen receptor	A,B	ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: ESR1, ESR, NR3A1

Authors :

Fanning, S.W., Greene, G.L.

Keywords :

Breast Cancer, Selective Estrogen Receptor Modulator, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 1.6464 Å )

Citation :

Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.

Maximov, P.Y.,Abderrahman, B.,Fanning, S.W. et al.
(2018) Mol. Pharmacol. 94 : 812 - 822

PDB ID: 5W9D