PDB ID: 5W8V
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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9YP | {[(2r)-2-[(2-amino-6-oxo-1,6-dihydro-9h-purin-9-yl)methyl]-3-(2-phosphonoethoxy)propoxy]methyl}phosphonic acid | PoSSuM | |||
MG | Magnesium ion | PoSSuM |
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Download interaction data: 5W8V
Structure summary
Code : | 5W8V PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | HUMAN HGPRT in complex with [(2-[(guanin-9-yl)methyl]propane-1,3-diyl)bis(oxy)]bis(methylene)diphosphonic acid | ||||||||||||
Release Data : | 2017-08-30 | ||||||||||||
Compound : |
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Authors : | Guddat, L.W., Keough, D.T. | ||||||||||||
Keywords : | 6-oxopurine; phosphoribosyltransferase; hypoxanthine; guanine; nucleoside phosphonate, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.346 Å ) | ||||||||||||
Citation : |
Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase.
Spacek, P.,Keough, D.T.,Chavchich, M.
et al.
PubMed: 28813147 |
Reaction
Chain : | A, B, C, D | ||||||||||||
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UniProt : | P00492 (HPRT_HUMAN) | ||||||||||||
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