PDB ID: 5W8L
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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NAI | 1,4-dihydronicotinamide adenine dinucleotide | PoSSuM | |||
9YA | 2-{3-([1,1'-biphenyl]-3-yl)-5-(cyclopropylmethyl)-4-[(4-sulfamoylphenyl)methyl]-1h-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM |
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Download interaction data: 5W8L
Structure summary
Code : | 5W8L PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 59 and NADH | ||||||||||||
Release Data : | 2018-01-17 | ||||||||||||
Compound : |
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Authors : | Davies, D.R., Dranow, D.M. | ||||||||||||
Keywords : | oxidoreductase, oxidoreductase inhibitor | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.9500 Å ) | ||||||||||||
Citation : |
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).
Rai, G.,Brimacombe, K.R.,Mott, B.T.
et al.
PubMed: 29120638 |
Reaction
Chain : | A, B, C, D | ||||||||
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UniProt : | P00338 (LDHA_HUMAN) | ||||||||
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