PDB ID: 5W84
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Structure summary
Code : | 5W84 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 4) | ||||||||||||
Release Data : | 2017-10-11 | ||||||||||||
Compound : |
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Source : |
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Authors : | Sack, J.S. | ||||||||||||
Keywords : | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.90 Å ) | ||||||||||||
Citation : |
Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors.
Bhide, R.S.,Keon, A.,Weigelt, C.
et al.
PubMed: 28947151 |
Reaction
Chain : | A, B | ||||||||||||
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UniProt : | Q9NWZ3 (IRAK4_HUMAN) | ||||||||||||
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