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Ligands
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9YM [4-({[(1r,2s,3s,4r,5s)-5-amino-2,3,4-trihydroxycyclohexyl]amino}methyl)-5-hydroxy-6-methylpyridin-3-yl]methyl dihydrogen phosphate
EDO 1,2-ethanediol
Non-standard Residues
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Code : 5W70   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : X-ray Structure of RbmB from Streptomyces ribosidificus
Release Data : 2017-07-12
Compound :
mol_id molecule chains synonym
1 L-glutamine:2-deoxy-scyllo-inosose aminotransferase A,B L-glutamine:DOI aminotransferase,L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase,L-glutamine:amino-DOI aminotransferase
ec: 2.6.1.100,2.6.1.101
Source :
mol_id organism_scientific expression_system
1 Streptomyces ribosidificus  (taxid:80859) Escherichia coli  (taxid:562)
atcc: 21294
gene: rbmB, rbcS, ribS
Authors : Zachman-Brockmeyer, T.R., Thoden, J.B., Holden, H.M.
Keywords : ribostamycin, aminotransferase, aminoglycoside, aminocyclitol antibiotic, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.10 Å )
Citation :

The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin.

Zachman-Brockmeyer, T.R.,Thoden, J.B.,Holden, H.M.
(2017)  Protein Sci.  26 : 1886 - 1892

PubMed: 28685903
DOI: 10.1002/pro.3221

Chain : A, B
UniProt : Q4R0W2 (GLDSA_STRRI)
Reaction: EC: Evidence:
Physiological Direction:
2-deoxy-L-scyllo-inosose + L-glutamine = 2-deoxy-scyllo- inosamine + 2-oxoglutaramate 2.6.1.100 UniProtKB:Q6L739
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3-amino-2,3-dideoxy-scyllo-inosose + L-glutamine = 2- deoxystreptamine + 2-oxoglutaramate 2.6.1.101 UniProtKB:Q6L739
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