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Ligands
Code Name Style Show Link
CL Chloride ion
GOL Glycerol
Non-standard Residues
Code Name Show
9WV Beta-alanyl-3-amino-L-alanine
MLE N-methylleucine
ORN L-ornithine
PH8 5-phenyl-L-norvaline
ZCL 3,4-dichloro-L-phenylalanine
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
ACE Acetyl group
Code : 5W6T   PDBj   RCSB PDB   PDBe
Header : VIRAL PROTEIN/PEPTIDE
Title : Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP151070 (P7)
Release Data : 2017-10-04
Compound :
mol_id molecule chains
1 Hemagglutinin A
fragment: residues 18-343
mol_id molecule chains
2 Hemagglutinin B
fragment: residues 344-519
mol_id molecule chains synonym
3 ACE-PH8-ORN-MLE-GLU-TYR-ZCL-GLU-TRP-LEU-SER-9WV F cyclic peptide CP151070 (P7)
Source :
mol_id organism_scientific expression_system
1 Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)  (taxid:211044) Trichoplusia ni  (taxid:7111)
strain: A/Puerto Rico/8/1934 H1N1
gene: HA
mol_id organism_scientific expression_system
2 Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)  (taxid:211044) Trichoplusia ni  (taxid:7111)
strain: A/Puerto Rico/8/1934 H1N1
gene: HA
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Wilson, I.A., Kadam, R.U.
Keywords : Glycoprotein, Ectodomain, N-glycosylation, VIRAL PROTEIN, VIRAL PROTEIN-PEPTIDE complex
Exp. method : X-RAY DIFFRACTION ( 2.59 Å )
Citation :

Potent peptidic fusion inhibitors of influenza virus.

Kadam, R.U.,Juraszek, J.,Brandenburg, B.  et al.
(2017)  Science  358 : 496 - 502

PubMed: 28971971
DOI: 10.1126/science.aan0516

Chain : B
UniProt : P03452 (HEMA_I34A1)
Reaction : -