PDB ID: 5W18
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 5W18 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE/ANTIBIOTIC | ||||||||||||||||||||||||
Title : | Staphylococcus aureus ClpP in complex with (S)-N-((2R,6S,8aS,14aS,20S,23aS)-2,6-dimethyl-5,8,14,19,23-pentaoxooctadecahydro-1H,5H,14H,19H-pyrido[2,1-I]dipyrrolo[2,1-C:2',1'-L][1]oxa[4,7,10,13]tetraazacyclohexadecin-20-yl)-3-phenyl-2-(3-phenylureido)propanamide | ||||||||||||||||||||||||
Release Data : | 2017-08-09 | ||||||||||||||||||||||||
Compound : |
|
||||||||||||||||||||||||
Source : |
|
||||||||||||||||||||||||
Authors : | Lee, R.E., Griffith, E.C. | ||||||||||||||||||||||||
Keywords : | ClpP, HYDROLASE-ANTIBIOTIC complex, UDEP | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.4400 Å ) | ||||||||||||||||||||||||
Citation : |
Ureadepsipeptides as ClpP Activators.
Griffith, E.C.,Zhao, Y.,Singh, A.P.
et al.
PubMed: 31588734 Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics.
Zhang, J.,Ye, F.,Lan, L.
et al.
PubMed: 21900233 Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.
Li, D.H.,Chung, Y.S.,Gloyd, M.
et al.
PubMed: 20851345 Insights into structural network responsible for oligomerization and activity of bacterial virulence regulator caseinolytic protease P (ClpP) protein.
Gersch, M.,List, A.,Groll, M.
et al.
PubMed: 22291011 |
Reaction
Chain : | A, B, C, D, E, F, G, I, K, L, M, N, S, T | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | Q2G036 (CLPP_STAA8) | ||||||||
|