Brand  (β version)

PDB ID: 5VU7

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Ligands
Code Name Style Show Link
FA2 5-(6-amino-9h-purin-9-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate PoSSuM
MG Magnesium ion PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
Code Name Show
9O4 (3r,5r)-5-(6-amino-9h-purin-9-yl)oxolan-3-yl dihydrogen phosphate
Glycosylation
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Modification
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Structure summary

Code : 5VU7   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE/DNA
Title : TNA polymerase, open ternary complex
Release Data : 2017-12-06
Compound :
mol_id molecule chains synonym
1 DNA polymerase A Kod-RI
ec: 2.7.7.7
mol_id molecule chains
2 DNA template T
mol_id molecule chains
3 DNA/TNA hybrid primer P
Source :
mol_id organism_scientific expression_system
1 Thermococcus kodakarensis  (taxid:311400) Escherichia coli  (taxid:562)
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Chim, N., Chaput, J.C.
Keywords : protein-nucleic acid complex, TRANSFERASE-DNA complex
Exp. method : X-RAY DIFFRACTION ( 2.720 Å )
Citation :

Structural basis for TNA synthesis by an engineered TNA polymerase.

Chim, N.,Shi, C.,Sau, S.P.  et al.
(2017)  Nat Commun  8 : 1810 - 1810

PubMed: 29180809
DOI: 10.1038/s41467-017-02014-0

Reaction

Chain : A
UniProt : D0VWU9 (D0VWU9_THEKO)
Reaction: EC: Evidence:
Physiological Direction:
DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate 2.7.7.7 ARBA:ARBA00049244, RuleBase:RU000442
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