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Ligands
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9GS 5'-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-N-{[4-(ethylsulfonyl)phenyl]methyl}spiro[cyclopentane-1,3'-pyrrolo[3,2-B]pyridine]-1'(2'H)-carboxamide
NA Sodium ion
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Code : 5VQL   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with a inverse agonist and SRC2 peptide
Release Data : 2018-05-16
Compound :
mol_id molecule chains synonym
1 Nuclear receptor ROR-gamma, SRC2 chimera A Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma,RORgt
fragment: residues 260-507
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
fragment: RORgt-LBD 260-507
gene: RORC, NR1F3, RORG, RZRG
expression_system_strain: BL21(DE3)
Authors : Li, X.
Keywords : NUCLEAR RECEPTOR, NUCLEAR HORMONE RECEPTOR, TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 2.70 Å )
Citation :

X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with a inverse agonist and SRC2 peptide

Li, X.
To Be Published 

Chain : A
UniProt : P51449 (RORG_HUMAN)
Reaction : -