PDB ID: 5VO2
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Structure summary
Code : | 5VO2 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE Inhibitor | ||||||||||||
Title : | DLK in complex with inhibitor 5-(1-isopropyl-5-(1-(oxetan-3-yl)piperidin-4-yl)-1H-pyrazol-3-yl)-3-(trifluoromethyl)pyridin-2-amine (compound 7) | ||||||||||||
Release Data : | 2017-10-04 | ||||||||||||
Compound : |
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Source : |
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Authors : | HARRIS, S.F., YIN, J. | ||||||||||||
Keywords : | kinase, TRANSFERASE-TRANSFERASE Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.9600 Å ) | ||||||||||||
Citation : |
Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease.
Patel, S.,Meilandt, W.J.,Erickson, R.I.
et al.
PubMed: 28929759 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q12852 (M3K12_HUMAN) | ||||||||||||
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