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Ligands
Code Name Style Show Link
ADE Adenine
MG Magnesium ion
PPV Pyrophosphate
HSX 5-O-phosphono-alpha-D-ribofuranose
Non-standard Residues
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Glycosylation
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Code : 5VN4   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of adenine phosphoribosyl transferase from Trypanosoma brucei in complex with AMP, pyrophosphate, and ribose-5-phosphate
Release Data : 2017-05-24
Compound :
mol_id molecule chains
1 Adenine phosphoribosyltransferase, putative A,B
ec: 2.4.2.7
fragment: TrbrA.01405.a.B1
Source :
mol_id organism_scientific expression_system
1 Trypanosoma brucei brucei (strain 927/4 GUTat10.1)  (taxid:185431) Escherichia coli  (taxid:469008)
strain: 927/4 GUTat10.1
gene: Tb927.7.1780
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
Authors : Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Keywords : SSGCID, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.3500 Å )
Citation :

Crystal structure of adenine phosphoribosyl transferase from Trypanosoma brucei in complex with AMP, pyrophosphate, and ribose-5-phosphate

Mayclin, S.J.,Dranow, D.M.,Lorimer, D.D.  et al.
to be published 

Chain : A, B
UniProt : Q57V32 (Q57V32_TRYB2)
Reaction: EC: Evidence:
Physiological Direction:
AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine 2.4.2.7 ARBA:ARBA00000868
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