PDB ID: 5VMP
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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NI | Nickel (II) ion | PoSSuM | |||
ZN | Zinc ion | PoSSuM | |||
9FJ | 3-({[(1r)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}amino)pyridine-4-carboxylic acid | PoSSuM |
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Download interaction data: 5VMP
Structure summary
Code : | 5VMP PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE/INHIBITOR | ||||||||||||
Title : | Crystal Structure of Human KDM4 with Small Molecule Inhibitor QC5714 | ||||||||||||
Release Data : | 2017-09-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Hosfield, D.J. | ||||||||||||
Keywords : | KDM4, Inhibitor-complex, demethylase, epigenetics, OXIDOREDUCTASE-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.4800 Å ) | ||||||||||||
Citation : |
Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.
Chen, Y.K.,Bonaldi, T.,Cuomo, A.
et al.
PubMed: 28835804 |
Reaction
Chain : | A, B, C, D | ||||||||||||
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UniProt : | O75164 (KDM4A_HUMAN) | ||||||||||||
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