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Ligands
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9EJ N-[(2s)-2-(diethylamino)propyl]-2-[(2s)-2-(methylcarbamoyl)azetidin-1-yl]-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide
DTT 2,3-dihydroxy-1,4-dithiobutane
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Glycosylation
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Code : 5VLO   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : The structure of human CamKII with bound inhibitor
Release Data : 2017-08-23
Compound :
mol_id molecule chains synonym
1 Calcium/calmodulin-dependent protein kinase type II subunit delta A,B CaMK-II subunit delta
ec: 2.7.11.17
fragment: UNP residues 3-301
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: CAMK2D, CAMKD
Authors : Somoza, J.R., Villasenor, A.G.
Keywords : Kinase, CamKII, inhibitor, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.05 Å )
Citation :

Inhibitors of CamKII

Somoza, T.J.,Villasenor, A.G.
To Be Published 

Chain : A, B
UniProt : Q13557 (KCC2D_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.17 -
-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.17 -
-