PDB ID: 5VKC
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Code | Name | Style | Show | Link | |
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9EA | 7-(3-{[4-(4-acetylpiperazin-1-yl)phenoxy]methyl}-1,5-dimethyl-1h-pyrazol-4-yl)-3-{3-[(naphthalen-1-yl)oxy]propyl}-1-[(pyridin-3-yl)methyl]-1h-indole-2-carboxylic acid | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 5VKC
Structure summary
Code : | 5VKC PDBj RCSB PDB PDBe | ||||||||||||
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Header : | signaling protein/inhibitor | ||||||||||||
Title : | Crystal structure of MCL-1 in complex with a BIM competitive inhibitor | ||||||||||||
Release Data : | 2017-05-03 | ||||||||||||
Compound : |
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Authors : | Judge, R.A., Souers, A.J. | ||||||||||||
Keywords : | MCL-1, signaling protein-inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3100 Å ) | ||||||||||||
Citation : |
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
Bruncko, M.,Wang, L.,Sheppard, G.S.
et al.
PubMed: 25679114 |
Reaction
Chain : | A, B |
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UniProt : | Q07820 (MCL1_HUMAN) |
Reaction : | - |