PDB ID: 5VDR
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Structure summary
Code : | 5VDR PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Human cyclic GMP-AMP synthase (cGAS) in complex with 3',3'-cdIMP | ||||||||||||
Release Data : | 2017-09-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Byrnes, L.J., Hall, J.D. | ||||||||||||
Keywords : | transferase, STING, cGAMP | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.0420 Å ) | ||||||||||||
Citation : |
The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Hall, J.,Ralph, E.C.,Shanker, S.
et al.
PubMed: 28940468 |
Reaction
Chain : | A, B | |||||||||
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UniProt : | Q8N884 (CGAS_HUMAN) | |||||||||
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