Het-PDB Navi2 (PDB: 5VBM)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
92V	1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxamide	PoSSuM
GDP	Guanosine-5'-diphosphate	PoSSuM
MG	Magnesium ion	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 5VBM

Code :

5VBM PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal Structure of Small Molecule Disulfide 2C07 Bound to K-Ras Cys Light M72C GDP

Release Data :

2017-10-25

Compound :

mol_id	molecule	chains	synonym
1	GTPase KRas	A	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
	mutation: M72C, C51S, C80L, C118S

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: KRAS, KRAS2, RASK2 expression_system_strain: BL21

Authors :

Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.

Keywords :

GTPase, Inhibitor, GDP, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 1.490 Å )

Citation :

Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.

Gentile, D.R.,Rathinaswamy, M.K.,Jenkins, M.L. et al.
(2017) Cell Chem Biol 24 : 1455 - 1466.e14

Chain :

UniProt :

P01116 (RASK_HUMAN)

PDB ID: 5VBM