PDB ID: 5V62
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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AKS | N-(hex-5-yn-1-yl)hexanamide | PoSSuM | |||
FRZ | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-C]pyridazin-3-amine | PoSSuM | |||
GOL | Glycerol | PoSSuM |
Code | Name | Show |
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AZK | (S)-2-amino-6-azidohexanoic acid | |
PTR | O-phosphotyrosine | |
TPO | Phosphothreonine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 5V62
Structure summary
Code : | 5V62 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE/INHIBITOR | ||||||||||||||||||||||||
Title : | Phospho-ERK2 bound to bivalent inhibitor SBP3 | ||||||||||||||||||||||||
Release Data : | 2017-07-26 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Lechtenberg, B.C., Riedl, S.J. | ||||||||||||||||||||||||
Keywords : | kinase, MAPK, phosphorylation, cancer, TRANSFERASE, TRANSFERASE-INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.9000 Å ) | ||||||||||||||||||||||||
Citation : |
Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
Lechtenberg, B.C.,Mace, P.D.,Sessions, E.H.
et al.
PubMed: 28740606 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P28482 (MK01_HUMAN) | ||||||||||||
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Chain : | I | ||||||||||||
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UniProt : | Q15418 (KS6A1_HUMAN) | ||||||||||||
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