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Ligands
Code Name Style Show Link
CO8 Octanoyl-coenzyme a
NA Sodium ion
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Code : 5V0P   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA
Release Data : 2017-03-22
Compound :
mol_id molecule chains synonym
1 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 A,B 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2,Beta-ketoacyl-ACP synthase III 2,KAS III 2
ec: 2.3.1.180
mutation: C113A
Source :
mol_id organism_scientific expression_system
1 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)  (taxid:243277) Escherichia coli  (taxid:562)
strain: ATCC 39315 / El Tor Inaba N16961
atcc: 39315
gene: fabH2, VC_A0751
expression_system_strain: BL21-CODONPLUS(DE3)-RIL
expression_system_vector_type: Plasmid
expression_system_plasmid: PMCSG7
Authors : Hou, J., Zheng, H., Cooper, D.R., Grabowski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Keywords : FABH, BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, TRANSFERASE, octanoyl-CoA, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID
Exp. method : X-RAY DIFFRACTION ( 2.16 Å )
Citation :

Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA

Hou, J.,Zheng, H.,Cooper, D.R.  et al.
To Be Published 

Chain : A, B
UniProt : Q9KLJ3 (FABH2_VIBCH)
Reaction: EC: Evidence:
Physiological Direction:
acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA 2.3.1.180 HAMAP-Rule:MF_01815
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