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Ligands
Code Name Style Show Link
RJW (1r,3ar,6ar)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol
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Code : 5UNJ   PDBj   RCSB PDB   PDBe
Header : NUCLEAR PROTEIN
Title : Structure of Human Liver Receptor Homolog 1 in complex with PGC1a and RJW100
Release Data : 2017-04-19
Compound :
mol_id molecule chains synonym
1 Nuclear receptor subfamily 5 group A member 2 A Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1
fragment: unp residues 299-541
mol_id molecule chains
2 Peroxisome proliferator-activated gamma coactivator 1-alpha C
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: NR5A2, B1F, CPF, FTF
mol_id organism_scientific
2 Homo sapiens  (taxid:9606)
synthetic: yes
Authors : Mays, S.G., Ortlund, E.A.
Keywords : Nuclear receptor, agonist, coregulator, NUCLEAR PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.9590 Å )
Citation :

Structure and Dynamics of the Liver Receptor Homolog 1-PGC1 alpha Complex.

Mays, S.G.,Okafor, C.D.,Tuntland, M.L.  et al.
(2017)  Mol. Pharmacol.  92 : 1 - 11

PubMed: 28363985
DOI: 10.1124/mol.117.108514

Chain : A
UniProt : O00482 (NR5A2_HUMAN)
Reaction : -