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Ligands
Code Name Style Show Link
9DA 9-deazaadenine
CA Calcium ion
CL Chloride ion
EDO 1,2-ethanediol
TRS 2-amino-2-hydroxymethyl-propane-1,3-diol
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Code : 5UE1   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with adenine from Vibrio fischeri ES114
Release Data : 2017-01-18
Compound :
mol_id molecule chains synonym
1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase A,B MTAN,5'-methylthioadenosine nucleosidase,MTA nucleosidase,S-adenosylhomocysteine nucleosidase,SRH nucleosidase
ec: 3.2.2.9
Source :
mol_id organism_scientific expression_system
1 Vibrio fischeri (strain ATCC 700601 / ES114)  (taxid:312309) Escherichia coli  (taxid:469008)
strain: ATCC 700601 / ES114
gene: mtnN, VF_2128
expression_system_strain: BL21 (DE3) magic
expression_system_vector_type: plasmid
expression_system_plasmid: pMCSG53
Authors : Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Grimshaw, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Keywords : Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, TRANSFERASE, NUCLEAR PROTEIN, Hydrolase
Exp. method : X-RAY DIFFRACTION ( 1.14 Å )
Citation :

Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Vibrio fischeri ES114

Filippova, E.V.,Minasov, G.,Shuvalova, L.  et al.
To Be Published 

Chain : A, B
UniProt : Q5E2X3 (MTNN_ALIF1)
Reaction: EC: Evidence:
Physiological Direction:
H2O + S-adenosyl-L-homocysteine = adenine + S-(5-deoxy-D- ribos-5-yl)-L-homocysteine 3.2.2.9 HAMAP-Rule:MF_01684
-
H2O + S-methyl-5'-thioadenosine = 5-(methylsulfanyl)-D-ribose + adenine 3.2.2.9 HAMAP-Rule:MF_01684
-
5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine 3.2.2.9 HAMAP-Rule:MF_01684
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