Brand  (β version)

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Ligands
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9CS (1r,2s,3s,4r,6s)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside
SAH S-adenosyl-L-homocysteine
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Code : 5U1E   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the kanamycin B
Release Data : 2017-11-01
Compound :
mol_id molecule chains
1 Putative gentamicin methyltransferase A
Source :
mol_id organism_scientific expression_system
1 Micromonospora echinospora  (taxid:1877) Escherichia coli BL21(DE3)  (taxid:469008)
gene: genN
Authors : Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
Keywords : gentamicin methyltransferase SAH kanamycin B, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.2130 Å )
Citation :

Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.

Bury, P.D.S.,Huang, F.,Li, S.  et al.
(2017)  ACS Chem. Biol.  12 : 2779 - 2787

PubMed: 28876898
DOI: 10.1021/acschembio.7b00466

Chain : A
UniProt : Q2MG72 (Q2MG72_MICEC)
Reaction : -