Brand  (β version)

PDB ID: 5TD4

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
CL Chloride ion PoSSuM
GLC Alpha-D-glucopyranose PoSSuM
: Polysaccharide
Non-standard Residues
Code Name Show
PCA Pyroglutamic acid
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 5TD4   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Starch binding sites on the Human pancreatic alpha amylase D300N variant complexed with an octaose substrate.
Release Data : 2016-11-02
Compound :
mol_id molecule chains synonym
1 Pancreatic alpha-amylase A PA,1,4-alpha-D-glucan glucanohydrolase
ec: 3.2.1.1
fragment: UNP residues 16-511
mutation: D300N
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Komagataella pastoris  (taxid:4922)
organ: Pancreas
gene: AMY2A
Authors : Caner, S., Brayer, G.D.
Keywords : Amylase, Diabetes, Obesity, Glucosyl hydrolase, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.300 Å )
Citation :

Evaluation of the Significance of Starch Surface Binding Sites on Human Pancreatic alpha-Amylase.

Zhang, X.,Caner, S.,Kwan, E.  et al.
(2016)  Biochemistry  55 : 6000 - 6009

PubMed: 27756128
DOI: 10.1021/acs.biochem.6b00992

Reaction

Chain : A
UniProt : P04746 (AMYP_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D- glucose units. 3.2.1.1 PubMed:10091666, PubMed:10769135, PubMed:11772019, PubMed:11914097
-