Het-PDB Navi2 (PDB: 5OUG)

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Ligands
Code	Name	Link
9Z0	4,5-dibromo-N-(3-hydroxypropyl)-1h-pyrrole-2-carboxamide	PoSSuM
DMS	Dimethyl sulfoxide	PoSSuM
L0B	Alpha-lobeline	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
BMA	Beta-D-mannopyranose
MAN	Alpha-D-mannopyranose
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
Code	Name	Show

Download interaction data: 5OUG

Code :

5OUG PDBj RCSB PDB PDBe

Header :

CHOLINE-BINDING PROTEIN

Title :

Humanized alpha-AChBP (acetylcholine binding protein) in complex with lobeline and allosteric binder fragment 4.

Release Data :

2017-12-20

Compound :

mol_id	molecule	chains	synonym
1	Humanized alpha-AChBP	A,B,C,D,E	Neuronal acetylcholine receptor subunit alpha-7

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Spodoptera frugiperda (taxid:7108)
	gene: CHRNA7, NACHRA7 expression_system_common: Fall armyworm expression_system_variant: RZ-2014

Authors :

Delbart, F., Gruss, F., Ulens, C.

Keywords :

acetylcholine binding protein, nicotinic acetylcholine receptor, CHOLINE-BINDING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.5700 Å )

Citation :

An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.

Delbart, F.,Brams, M.,Gruss, F. et al.
(2018) J. Biol. Chem. 293 : 2534 - 2545

PDB ID: 5OUG