Het-PDB Navi2 (PDB: 5OR8)

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Ligands
Code	Name		Style	Show	Link
JR4	~{N}-[(4-fluorophenyl)methyl]-1,3,6-trimethyl-2-oxidanylidene-benzimidazole-5-sulfonamide				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5OR8

Code :

5OR8 PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Crystal Structure of BAZ2A bromodomain in complex with 1,3-dimethyl-benzimidazolone compound 1

Release Data :

2017-09-13

Compound :

mol_id	molecule	chains	synonym
1	Bromodomain adjacent to zinc finger domain protein 2A	A	Transcription termination factor I-interacting protein 5,Tip5,hWALp3
	fragment: Bromodomain, UNP residues 1796-1899 mutation: First two residues SM derive from the expression tag other_details: First two residues SM derive from the expression tag

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: BAZ2A, KIAA0314, TIP5

Authors :

Lolli, G., Dalle Vedove, A., Marchand, J.-R., Caflisch, A.

Keywords :

four helical bundle, transcription

Exp. method :

X-RAY DIFFRACTION ( 2.4000 Å )

Citation :

Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking.

Marchand, J.R.,Dalle Vedove, A.,Lolli, G. et al.
(2017) J Chem Inf Model 57 : 2584 - 2597

PDB ID: 5OR8