Brand  (β version)

PDB ID: 5OLV

Hetero Atom Contents

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Ligands
Code Name Style Show Link
9Y2 4-(3,3-dimethylbutanoylamino)-3,5-bis(fluoranyl)-~{N}-(1,3-thiazol-2-yl)benzamide PoSSuM
CLR Cholesterol PoSSuM
NA Sodium ion PoSSuM
OLA Oleic acid PoSSuM
OLC (2r)-2,3-dihydroxypropyl (9z)-octadec-9-enoate PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5OLV   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Structure of the A2A-StaR2-bRIL562-LUAA47070 complex at 2.0A obtained from in meso soaking experiments.
Release Data : 2018-01-17
Compound :
mol_id molecule chains synonym
1 Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a A Cytochrome b-562
mutation: A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A,A54L; T88A; R107A; K122A; L202A; L235A; V239A; S277A; N154A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Trichoplusia ni  (taxid:7111)
gene: ADORA2A, ADORA2
expression_system_common: Cabbage looper
expression_system_vector_type: Virus
Authors : Rucktooa, P., Cheng, R.K.Y., Segala, E., Geng, T., Errey, J.C., Brown, G.A., Cooke, R., Marshall, F.H., Dore, A.S.
Keywords : G-Protein Coupled Receptor, Adenosine 2a receptor, 7 TM integral membrane protein, thermostabilizing mutations, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.998 Å )
Citation :

Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.

Rucktooa, P.,Cheng, R.K.Y.,Segala, E.  et al.
(2018)  Sci Rep  8 : 41 - 41

PubMed: 29311713
DOI: 10.1038/s41598-017-18570-w

Reaction

Chain : A
UniProt : P29274 (AA2AR_HUMAN)
Reaction : -
Chain : A
UniProt : P0ABE7 (C562_ECOLX)
Reaction : -
Cofactor: Evidence: Note:
heme b - Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.