PDB ID: 5OIA
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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9VK | (2~{S})-2-[4-(4,4-dimethylcyclohexen-1-yl)-2-methyl-5-pyridin-2-yl-thiophen-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid | PoSSuM | |||
MG | Magnesium ion | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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CAS | S-(dimethylarsenic)cysteine |
Code | Name | Emphasize |
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Download interaction data: 5OIA
Structure summary
Code : | 5OIA PDBj RCSB PDB PDBe | ||||||||||||
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Header : | VIRAL PROTEIN | ||||||||||||
Title : | Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1 | ||||||||||||
Release Data : | 2018-03-07 | ||||||||||||
Compound : |
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Source : |
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Authors : | Ruff, M., Benarous, R. | ||||||||||||
Keywords : | HIV-1, Integrase, Catalytic core domain, VIRAL PROTEIN | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.20 Å ) | ||||||||||||
Citation : |
Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration.
Bonnard, D.,Le Rouzic, E.,Eiler, S.
et al.
PubMed: 29507092 |
Reaction
Chain : | A |
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UniProt : | I0BY59 (I0BY59_9HIV1) |
Reaction : | - |