Het-PDB Navi2 (PDB: 5OI8)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
9VN	(2~{S})-2-[4-(4,4-dimethylcyclohexen-1-yl)-2-methyl-5-pyridin-4-yl-thiophen-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid	PoSSuM
MG	Magnesium ion	PoSSuM
SO4	Sulfate ion	PoSSuM

Non-standard Residues
Code	Name	Show
CAS	S-(dimethylarsenic)cysteine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 5OI8

Code :

5OI8 PDBj RCSB PDB PDBe

Header :

VIRAL PROTEIN

Title :

Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1

Release Data :

2018-03-07

Compound :

mol_id	molecule	chains
1	Pol protein	A

Source :

mol_id	organism_scientific	expression_system
1	Human immunodeficiency virus 1 (taxid:11676)	Escherichia coli (taxid:562)
	gene: pol

Authors :

Ruff, M., Benarous, R.

Keywords :

HIV-1, Integrase, Catalytic core domain, VIRAL PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.35 Å )

Citation :

Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration.

Bonnard, D.,Le Rouzic, E.,Eiler, S. et al.
(2018) J. Biol. Chem. 293 : 6172 - 6186

PDB ID: 5OI8