Brand  (β version)

PDB ID: 5OGW

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Ligands
Code Name Style Show Link
9UE Jasplakinolide PoSSuM
ADP Adenosine-5'-diphosphate PoSSuM
MG Magnesium ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5OGW   PDBj   RCSB PDB   PDBe
Header : STRUCTURAL PROTEIN
Title : Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution
Release Data : 2017-09-27
Compound :
mol_id molecule chains synonym
1 Actin-1 A,B,C,D,E Actin I,PfACT1
Source :
mol_id organism_scientific expression_system
1 Plasmodium falciparum (isolate HB3)  (taxid:137071) Spodoptera frugiperda  (taxid:7108)
strain: isolate HB3
Authors : Pospich, S., Kumpula, E.-P., von der Ecken, J., Vahokoski, J., Kursula, I., Raunser, S.
Keywords : F-actin, Plasmodium, malaria parasite, cytoskeleton, cryo-EM, JAS, Jasplakinolide, filament, glideosome, gliding motility, thin filament, structural protein
Exp. method : ELECTRON MICROSCOPY ( 3.8 Å )
Citation :

Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.

Pospich, S.,Kumpula, E.P.,von der Ecken, J.  et al.
(2017)  Proc. Natl. Acad. Sci. U.S.A.  114 : 10636 - 10641

PubMed: 28923924
DOI: 10.1073/pnas.1707506114

Reaction

Chain : A, B, C, D, E
UniProt : P86287 (ACT1_PLAFX)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O = ADP + H(+) + phosphate - UniProtKB:Q8I4X0
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