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Ligands
Code Name Style Show Link
DMS Dimethyl sulfoxide
FLK 3-chloranyl-~{N}'-(4,5-dihydro-1~{H}-imidazol-3-ium-2-yl)propanehydrazide
Non-standard Residues
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Glycosylation
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Code : 5OG7   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Endothiapepsin in complex with hydrazide fragment
Release Data : 2018-08-08
Compound :
mol_id molecule chains synonym
1 Endothiapepsin A Aspartate protease
ec: 3.4.23.22
Source :
mol_id organism_scientific organism_common
1 Cryphonectria parasitica  (taxid:5116) Chestnut blight fungus
Authors : Metz, A., Klauser, P.C., Heine, A., Klebe, G.
Keywords : fragment, inhibitor, hydrazide, complex, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.823 Å )
Citation :

Endothiapepsin in complex with hydrazide fragment

Metz, A.,Klauser, P.C.,Rudek, M.  et al.
To Be Published 

Chain : A
UniProt : P11838 (CARP_CRYPA)
Reaction: EC: Evidence:
Physiological Direction:
Hydrolysis of proteins with specificity similar to that of pepsin A, prefers hydrophobic residues at P1 and P1', but does not cleave 14-Ala-|-Leu-15 in the B chain of insulin or Z-Glu-Tyr. Clots milk. 3.4.23.22 -
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