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Ligands
Code Name Style Show Link
9SZ (1r,5s,9s,16r,20r,24s,28s,35r)-3,22-bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene
CL Chloride ion
GOL Glycerol
Non-standard Residues
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Code : 5OEH   PDBj   RCSB PDB   PDBe
Header : SIGNALING PROTEIN
Title : Molecular tweezers modulate 14-3-3 protein-protein interactions.
Release Data : 2017-07-26
Compound :
mol_id molecule chains synonym
1 14-3-3 protein sigma A Epithelial cell marker protein 1,Stratifin
other_details: GAMGS - cleavage artifact
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: SFN, HME1
Authors : Bier, D., Ottmann, C.
Keywords : 14-3-3 Protein, Inhibition, supramolecular ligands, SIGNALING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.3500 Å )
Citation :

Molecular tweezers modulate 14-3-3 protein-protein interactions.

Bier, D.,Rose, R.,Bravo-Rodriguez, K.  et al.
(2013)  Nat Chem  5 : 234 - 239

PubMed: 23422566
DOI: 10.1038/nchem.1570

Chain : A
UniProt : P31947 (1433S_HUMAN)
Reaction : -