Het-PDB Navi2 (PDB: 5OBH)

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Ligands
Code	Name		Style	Show	Link
CL	Chloride ion				PoSSuM
J94	(5s)-6,6-dimethyl-5-[(6r)-8-oxo-6,8-dihydrofuro[3,4-E][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-G]isoquinolin-6-ium				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
Code	Name	Show

Download interaction data: 5OBH

Code :

5OBH PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

Crystal structure of glycine binding protein in complex with bicuculline

Release Data :

2018-08-01

Compound :

mol_id	molecule	chains	synonym
1	Soluble acetylcholine receptor	A,B,C,D,E	Glycine binding protein
	mutation: T53F, Q74R, Y110A, I135S, G162E, S206K, C207G, C208T, P209G

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Aplysia californica (taxid:6500)	California sea hare	Spodoptera frugiperda (taxid:7108)
	expression_system_common: Fall armyworm expression_system_cell_line: Sf9

Authors :

Dawson, A., Hunter, W.N., Jones, M.

Keywords :

receptor, acetylcholine binding, SIGNALING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.40 Å )

Citation :

A Structural Rationale for N-Methylbicuculline Acting as a Promiscuous Competitive Antagonist of Inhibitory Pentameric Ligand-Gated Ion Channels.

Jones, M.J.,Dawson, A.,Hales, T.G. et al.
(2020) Chembiochem 21 : 1526 - 1533

PDB ID: 5OBH