Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
9LN 1-ethyl-~{N}-methyl-2,3-bis(oxidanylidene)-~{N}-[(1-phenylpyrazol-4-yl)methyl]-4~{H}-quinoxaline-6-carboxamide
NO3 Nitrate ion
Code : 5O5A
Header : DNA BINDING PROTEIN
Title : Crystal structure of the human BRPF1 bromodomain in complex with BZ032
Release Data : 2018-06-13
Compound :
mol_id molecule chains synonym
1 Peregrin A Bromodomain and PHD finger-containing protein 1,Protein Br140
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: BRPF1, BR140
Authors : Zhu, J., Caflisch, A.
Keywords : Bromodomain and PHD finger-containing protein 1(BRPF1), monocytic leukemia zinc-finger (MOZ), Inhibitor, transcription, DNA binding protein
Exp. method : X-RAY DIFFRACTION ( 1.600 Å )
Citation :

Structure-based discovery of selective BRPF1 bromodomain inhibitors.

Zhu, J.,Zhou, C.,Caflisch, A.
(2018)  Eur J Med Chem  155 : 337 - 352

PubMed: 29902720
DOI: 10.1016/j.ejmech.2018.05.037

Chain : A
UniProt : P55201 (BRPF1_HUMAN)
Reaction : -