Het-PDB Navi2 (PDB: 5O4V)

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Ligands
Code	Name	Link
NHW	2-oxopentadecyl-CoA	PoSSuM
9K2	1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine	PoSSuM
DMS	Dimethyl sulfoxide	PoSSuM
MG	Magnesium ion	PoSSuM
CL	Chloride ion	PoSSuM
SO4	Sulfate ion	PoSSuM
9KZ	Ethyl 2,4-dimethylquinoline-3-carboxylate	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5O4V

Code :

5O4V PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

P.vivax NMT with aminomethylindazole and quinoline inhibitors bound

Release Data :

2018-05-16

Compound :

mol_id	molecule	chains
1	Glycylpeptide N-tetradecanoyltransferase	A,B,C
	ec: 2.3.1.97

Source :

mol_id	organism_scientific	expression_system
1	Plasmodium vivax (taxid:5855)	Escherichia coli BL21(DE3) (taxid:469008)
	gene: PVX_085815 expression_system_variant: plysS expression_system_vector_type: pET

Authors :

Brannigan, J.A., Wilkinson, A.J.

Keywords :

TRANSFERASE, INHIBITOR, MYRISTOYL

Exp. method :

X-RAY DIFFRACTION ( 1.70 Å )

Citation :

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.

Mousnier, A.,Bell, A.S.,Swieboda, D.P. et al.
(2018) Nat Chem 10 : 599 - 606

PDB ID: 5O4V