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Ligands
Code Name Style Show Link
9KH 6-carboxy methyl-4-hydroxy-2-pyridinol
DMS Dimethyl sulfoxide
MPD (4s)-2-methyl-2,4-pentanediol
SAH S-adenosyl-L-homocysteine
Non-standard Residues
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Code : 5O4N   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Apo HcgC from Methanococcus maripaludis soaked with SAH and pyridinol
Release Data : 2017-07-19
Compound :
mol_id molecule chains
1 HcgC A,B,C,D
Source :
mol_id organism_scientific expression_system
1 Methanococcus maripaludis S2  (taxid:267377) Escherichia coli BL21(DE3)  (taxid:469008)
cell_line: /
atcc: /
organ: /
tissue: /
cell: /
gene: MMP1498
expression_system_variant: Star
expression_system_atcc_number: /
expression_system_organ: /
expression_system_tissue: /
expression_system_cell: /
expression_system_vector_type: Plasmid
expression_system_vector: pET24b(+)
Authors : Wagner, T., Bai, L., Xu, T., Hu, X., Ermler, U., Shima, S.
Keywords : methyltransferases, biosynthesis, protein structures, enzyme catalysis, mutagenesis, [Fe]-hydrogenase, pyridinol, Hmd, Transferase
Exp. method : X-RAY DIFFRACTION ( 2.05 Å )
Citation :

A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC.

Bai, L.,Wagner, T.,Xu, T.  et al.
(2017)  Angew. Chem. Int. Ed. Engl.  56 : 10806 - 10809

PubMed: 28682478
DOI: 10.1002/anie.201705605

Chain : A, B, C, D
UniProt : Q6LX54 (Q6LX54_METMP)
Reaction : -