Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
9JK ~{N}-phenyl-2-sulfanyl-benzamide
SO4 Sulfate ion
ZN Zinc ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 5O3Y   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : SOD1 bound to Ebsulfur
Release Data : 2018-06-13
Compound :
mol_id molecule chains synonym
1 Superoxide dismutase [Cu-Zn] A,F Superoxide dismutase 1,hSod1
ec: 1.15.1.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: SOD1
expression_system_plasmid: pET26b
Authors : Capper, M.J., Wright, G.S.A., Antonyuk, S.V., Hasnain, S.S.
Keywords : OXIDOREDUCTASE Drug discovery ALS MND, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.30 Å )
Citation :

The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.

Capper, M.J.,Wright, G.S.A.,Barbieri, L.  et al.
(2018)  Nat Commun  9 : 1693 - 1693

PubMed: 29703933
DOI: 10.1038/s41467-018-04114-x

Chain : A, F
UniProt : P00441 (SODC_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
2 H(+) + 2 superoxide = H2O2 + O2 1.15.1.1 PubMed:24140062
-