Brand  (β version)

PDB ID: 5NZW

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Ligands
Code Name Style Show Link
9F2 Ceftriaxone PoSSuM
NI Nickel (II) ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 5NZW   PDBj   RCSB PDB   PDBe
Header : DNA BINDING PROTEIN
Title : Crystal structure of DNA cross-link repair protein 1A in complex with ceftriaxone
Release Data : 2017-06-14
Compound :
mol_id molecule chains synonym
1 DNA cross-link repair 1A protein A SNM1 homolog A,hSNM1A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: DCLRE1A, KIAA0086, SNM1, SNM1A
expression_system_common: Fall armyworm
expression_system_vector_type: baculovirus
Authors : Newman, J.A., Aitkenhead, H., Kupinska, K., Burgess-Brown, N.A., Talon, R., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
Keywords : exonulcease, cephalosporin, cross-link repair, DCLRE1A, DNA binding protein
Exp. method : X-RAY DIFFRACTION ( 2.70 Å )
Citation :

Crystal structure of DNA cross-link repair protein 1A in complex with ceftriaxone

Newman, J.A.,Aitkenhead, H.,Kupinska, K.  et al.
To Be Published 

Reaction

Chain : A
UniProt : Q6PJP8 (DCR1A_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
a beta-lactam + H2O = a substituted beta-amino acid 3.5.2.6 PubMed:31434986
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