Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
9D8 4-[(3-chlorophenyl)sulfamoyl]-~{N}-(phenylmethyl)-~{N}-propyl-benzamide
EDO 1,2-ethanediol
Code : 5NXD
Header : TRANSFERASE
Title : LIM Domain Kinase 2 (LIMK2) In Complex With TH-300
Release Data : 2017-05-24
Compound :
mol_id molecule chains synonym
1 LIM domain kinase 2 A,B LIMK-2
ec: 2.7.11.1
fragment: UNP residues 330-632
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: LIMK2
expression_system_common: Fall armyworm
Authors : Mathea, S., Salah, E., Hanke, T., Newman, J.A., Oerum, S., Wang, D., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N., Knapp, S.
Keywords : Kinase Actin cytoskeleton Inhibitor DFG-out, transferase
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

LIM Domain Kinase 2 (LIMK2)In Complex With TH-300

Mathea, S.,Salah, E.,Hanke, T.  et al.
To Be Published 

Chain : A, B
UniProt : P53671 (LIMK2_HUMAN)
Reaction : ATP + a protein = ADP + a phosphoprotein.